Fully automated testing
Qualitative analysis with fast separation and good resolution of serum and urine samples.
About Serum and Urine Immunotyping
Immunotyping is used to detect and identify monoclonal proteins in serum and urine. Serum and urine proteins are mixed with specific antisera against Gamma- (IgG), Alpha- (IgA), Mu- (IgM) heavy chains Kappa (κ) and Lambda (λ) free and bound light chains.
Immunoglobulins specifically react with their corresponding antiserum and each antiserum pattern (IgG, IgA, IgM, κ and λ) is automatically overlaid with the ELP (Protein Electrophoresis) reference curve. Disappearance of the abnormality in the antiserum-treated pattern indicates the presence of a monoclonal protein.
Pathologies
Technologies
Key benefits
Serum and Urine Immunotyping powered by Capillary Electrophoresis.
Direct visualisation of serum protein profile
for quick identification of suspect monoclonal proteins (IgG, IgA, IgM, Kappa (κ) and Lambda (λ)) involved in gammopathy.
High quality of antisera ready to use
for an optimum reaction performance and correct monoclonal component identification.
Scalable solutions
to best fit the need for all sized laboratories, from a standalone instrument to workcell configuration.
Main characteristics
Test principle
- Based on the principle of capillary electrophoresis in free solution. Serum or Urine proteins are mixed with specific antisera.
- Immunoglobulins specifically react with their corresponding antiserum. At the end of the analysis, each antiserum pattern (IgG, IgA, IgM, κ and λ) is automatically overlaid with the ELP (Protein Electrophoresis) reference curve.
- Disappearance of the abnormality in the antiserum-treated pattern indicates the presence of a monoclonal protein.
Sample type
Serum & Urine
Performances
- Full traceability and positive sample ID from primary tube samples
- Full traceability and reagents management through RFID tags for both reagents and antisera
- On board antisera vials kept at cool temperature
- Full automation
- Color-coded backlit reagent containers
Sensitivity
- Monoclonal protein can be detected at a concentration as low as 12.5 mg/dL in serum. According to the mobility of the monoclonal component and polyclonal background, the sensitivity may vary.
- Protein abnormality limit of detection is approximately 9 mg/L with CAPI 3 URINE.
Throughput
*Throughput (tests/hour)
IMMUNOTYPING
CAPILLARYS 3 OCTA (serum or urine) 9
CAPILLARYS 3 TERA (serum or urine) 12
CAPILLARYS 3 TERA MC3 (serum or urine) 34
MINICAP FLEX-PIERCING (serum) 2
*Firmware-dependent; contact your local Sebia representative for current information.
Product details
- CAPI 3 IMMUNOTYPING – P/N: 2600
- MINICAP IMMUNOTYPING – P/N: 2300
Knowledge & Science
No content available.
Serum and Urine Immunotyping tests can be performed on the following instruments
The compact and affordable automation of Capillary Electrophoresis.
Capillary Electrophoresis solution to meet your high capacity needs.
A concentrate of Sebia’s expertise in a high throughput instrument.
Tests related to Serum and Urine Immunotyping
This section contains information intended for wide distribution and may therefore contain product details or information that is not available or valid in your country. Please contact your local Sebia representative. Information intended for healthcare professionals. Carefully read the instructions in the reagent package inserts and instrument manuals.